FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Mi-2, Top2
FlyBase ID
FBig0000107337
Interaction Network
Interactions Browser links
Mi-2 network
Top2 network
Reported Interactions
FBrf0228621-17.coIP.WB
Reference
Cugusi et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Mi-2 

Mi-2

bait
Top2 

Topo II

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Mi-2 binds Top2 in an RNA-dependent manner; the interaction is disrupted by RNase treatment.

(Cugusi et al., 2015)

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Cugusi et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)