FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Ptpmeg, Pvr
FlyBase ID
FBig0000107596
Interaction Network
Interactions Browser links
Ptpmeg network
Pvr network
Reported Interactions
FBrf0229035-3.coIP.MS
Reference
Li et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Ptpmeg 

dPtpmeg

bait

HA tag

Ptpmeg 
Ptpmeg 
Pvr 

Pvr

prey

5 peptides identified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Ptpmeg 
catalytic domain
sufficient binding region
aa 615-974

coordinates relative to Ptpmeg-PA (reported as aa 497-856)

Ptpmeg 
catalytic domain residue D809
mutation increasing interaction
aa 809

D809A, coordinates relative to Ptpmeg-PG (reported as D691A)

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

An enzymatically inactive version of the Ptpmeg catalytic domain was used to trap substrates.

(Li et al., 2015)

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from S2 cell extract.

(Li et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)