FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Spt6, Polr2A
FlyBase ID
FBig0000107742
Interaction Network
Interactions Browser links
Spt6 network
Polr2A network
Reported Interactions
FBrf0161558-2.coIP.WB
Reference
Saunders et al., 2003
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Spt6 

Spt6

bait
Polr2A 

RpII215

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Immunoprecipitated Pol II was recognized by antibodies specific for both Ser2 and Ser5 phosphorylated versions.

(Saunders et al., 2003)

Source was unspecified Drosophila cell extract; bait produced from endogenous gene; prey produced from endogenous gene.

(Saunders et al., 2003)
FBrf0234283-1.coIP.WB
Reference
Choudhury et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Polr2A 

RNA Pol II

bait
Spt6 

Spt6

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Choudhury et al., 2016)

Positive control.

(Choudhury et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)