FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Ssrp, Su(var)205
FlyBase ID
FBig0000108323
Interaction Network
Interactions Browser links
Ssrp network
Su(var)205 network
Reported Interactions
FBrf0212000-1.TAP.MP
Reference
Kwon et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Su(var)205 

Su(var)205

bait

HA, FLAG tag

Ssrp 

Ssrp

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Kwon et al., 2010)
FBrf0212000-10.coIP.WB
Reference
Kwon et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Ssrp 

Ssrp

bait
Su(var)205 

Su(var)205

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Kwon et al., 2010)
FBrf0212000-19.PD.WB
Reference
Kwon et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Su(var)205 

Su(var)205

bait

GST tag

Su(var)205 
Ssrp 

Ssrp

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Su(var)205 
CSD domain
sufficient binding region
aa 141-206
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; recombinant proteins produced in baculovirus and insect cell system.

(Kwon et al., 2010)
FBrf0212000-20.PD.WB
Reference
Kwon et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ssrp 

Ssrp

bait

GST tag

Su(var)205 

Su(var)205

prey

HA tag

Su(var)205 
Su(var)205 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Su(var)205 
region residue 191
mutation decreasing interaction
aa 191

I191E

Su(var)205 
region residue 200
mutation decreasing interaction
aa 200

W200A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; recombinant proteins produced in baculovirus and insect cell system.

(Kwon et al., 2010)
FBrf0212000-8.coIP.WB
Reference
Kwon et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ssrp 

Ssrp

bait

HA tag

Su(var)205 

Su(var)205

prey

FLAG or GST tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; recombinant proteins produced in baculovirus and insect cell system.

(Kwon et al., 2010)
FBrf0241416-29.PD.WB
Reference
Lee et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ssrp 

dSSRP1

bait

HA tag

Su(var)205 

HP1a

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control.

(Lee et al., 2019)

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial or baculoviral system; prey produced as a recombinant fusion protein in bacterial or baculoviral system.

(Lee et al., 2019)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)