FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
aub, nanos
FlyBase ID
FBig0000108714
Interaction Network
Interactions Browser links
aub network
nanos network
Reported Interactions
FBrf0212183-7.coIP.PCR
Reference
Rouget et al., 2010
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
aub 

aub

bait
nanos 

nos

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Rouget et al., 2010)

Interaction also detected in osk mutant background.

(Rouget et al., 2010)
FBrf0212348-1.coIP.PCR
Reference
Becalska et al., 2011
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
aub 

aub

bait

FLAG tag

nanos 

nos

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Becalska et al., 2011)
FBrf0229314-1.ICLIP.SEQ
Reference
Barckmann et al., 2015
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
aub 

aub

bait

GFP tag

nanos 

nos

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Barckmann et al., 2015)
FBrf0235333-8.ICLIP.SEQ
Reference
Ma et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
fGS/OSS
Participants
Corresponds to
Reported as
Role
Note
aub 

aub

bait

GFP tag

nanos 

nos

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was fGS/OSS cells derived from adult female ovary; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Ma et al., 2017)
FBrf0260575-8.coIP.PCR
Reference
Rojas-Ríos et al., 2024
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
aub 

aub

bait

GFP tag

aub 
nanos 

nanos

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
aub 
PAZ domain residues 345 and 346
necessary binding region
aa 345-346

Y345A, Y346A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control

(Rojas-Ríos et al., 2024)

Source was adult female ovaries; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Rojas-Ríos et al., 2024)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (5)