FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Rab1, GM130
FlyBase ID
FBig0000109373
Interaction Network
Interactions Browser links
Rab1 network
GM130 network
Reported Interactions
FBrf0206354-15.Y2H
Reference
Sinka et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab1 

Rab1

bait

fused to GAL4 DNA-binding domain

GM130 

dGM130

prey

fused to GAL4 activation domain

GM130 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
GM130 
N-terminal region
sufficient binding region
aa 1-550
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Sinka et al., 2008)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Sinka et al., 2008)
FBrf0235214-6.coIP.WB
Reference
Liu et al., 2017
Description
physical association
Assay
Collection
Source/Stage
fat body / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab1 

Rab1

bait

YFP tag

GM130 

GM130

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval fat bodies of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Liu et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)