FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
vkg, dpp
FlyBase ID
FBig0000109540
Interaction Network
Interactions Browser links
vkg network
dpp network
Reported Interactions
FBrf0218813-1.PD.WB
Reference
Sawala et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
vkg 

vkg

bait

GST tag

dpp 

dpp

prey

HA tag

dpp 
dpp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dpp 
interaction domain
sufficient binding region
aa 457-484

coordinates relative to dpp-PB

dpp 
basic domain
necessary binding region
aa 469-479

coordinates relative to dpp-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced from transfected construct.

(Sawala et al., 2012)

Addition of scw increases interaction. Addition of sog allows interaction between vkg and mutant dpp with residues 469-479 deleted.

(Sawala et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)