FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000115883
Interaction Network
Interactions Browser links
Asx network
trx network
Reported Interactions
FBrf0236724-1.PD.A
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
trx 

Trx

bait

GST tag

trx 
Asx 

Asx

prey

[35]S label

Asx 
Asx 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
trx 
SET domain
sufficient binding region
aa 3608-3759

coordinates cannot be mapped to either 3726aa or 3358aa isoform.

Asx 
interaction domain
sufficient binding region
aa 1-354aa 1200-1501aa 1501-1669

coordinates relative to Asx-PA

coordinates relative to Asx-PA

coordinates relative to Asx-PA

Asx 
interaction domain
necessary binding region
aa 1-199aa 1200-1380

coordinates relative to Asx-PA

coordinates relative to Asx-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

FBrf0236724-3.CH.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
trx 

Trx

neutral component
trx 

Trx

neutral component
trx 

Trx

neutral component
Asx 

Asx

neutral component
Asx 

Asx

neutral component
Asx 

Asx

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; proteins produced from endogenous genes.

FBrf0236724-4.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Asx 

Asx

bait
trx 

Trx

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

FBrf0236724-7.PLA
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Asx 

Asx

neutral component
Asx 

Asx

neutral component
Asx 

Asx

neutral component
trx 

Trx

neutral component
trx 

Trx

neutral component
trx 

Trx

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; proteins produced from endogenous gene.

The PLA signal develops only if probes to the two factors are in close proximity to each other (within tens of nanometers).

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)