FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Gprk2, Cul4
FlyBase ID
FBig0000116699
Interaction Network
Interactions Browser links
Gprk2 network
Cul4 network
Reported Interactions
FBrf0239705-3.coIP.WB
Reference
Li et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Gprk2 

Gprk2

bait

Myc tag

Cul4 

Cul4

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Treatment of cells with hh conditioned medium or smo RNAi or a combination of Gβ13F and Gβ76C RNAi diminished the Gprk2-Cul4 interaction.

(Li et al., 2018)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)