FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
srp, MED1
FlyBase ID
FBig0000118217
Interaction Network
Interactions Browser links
srp network
MED1 network
Reported Interactions
FBrf0241861-1.coIP.WB
Reference
Immarigeon et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
MED1 

Med1

bait
srp 

Srp

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Kc167 cell line; bait produced from endogenous gene; prey produced from transfected construct.

(Immarigeon et al., 2019)
FBrf0241861-5.coIP.WB
Reference
Immarigeon et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
srp 

Srp

bait

GFP tag

MED1 

Med1

prey
MED1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Kc167 cell line; bait produced from endogenous gene; prey produced from transfected construct.

(Immarigeon et al., 2019)
FBrf0241861-6.PD.A
Reference
Immarigeon et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
MED1 

Med1

bait

GST tag

MED1 
srp 

Srp

prey

[35]S label

srp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
MED1 
exon4
sufficient binding region
unspecified

fragment of MED1-PA corresponding to exon 4.

srp 
Zn-finger domain
sufficient binding region
aa 365-530
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Immarigeon et al., 2019)
External Crossreferences and Linkouts ( 0 )
References (1)