FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mahj, pic
FlyBase ID
FBig0000119802
Interaction Network
Interactions Browser links
mahj network
pic network
Reported Interactions
FBrf0242621-4.coIP.WB
Reference
Ly et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
pic 

DDB1

bait

Myc or Venus tag

mahj 

Mahj

prey

Myc, HA or Venus tag

mahj 
mahj 
mahj 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mahj 
HLH-WD40 domain
sufficient binding region
aa 1096-1447

coordinates relative to mahj-PA

mahj 
HLH domain
mutation disrupting interaction
aa 1120,1123

R1120E,R1123E, coordinates relative to mahj-PA

mahj 
WD40 domain
mutation disrupting interaction
aa 1307,1343

R1307A,R1343A, coordinates relative to mahj-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ly et al., 2019)
FBrf0242621-5.coIP.WB
Reference
Ly et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mahj 

Mahj

bait

Venus tag

pic 

DDB1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ly et al., 2019)
External Crossreferences and Linkouts ( 0 )
References (1)