FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
elav, Dscam1
FlyBase ID
FBig0000119868
Interaction Network
Interactions Browser links
elav network
Dscam1 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0242770-2.coIP.PCR
Reference
Zhang et al., 2019
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
elav 

Elav

bait
Dscam1 

Dscam1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Zhang et al., 2019)
FBrf0242770-3.EMSA.A
Reference
Zhang et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
elav 

Elav

bait

GST tag

Dscam1 

Dscam1

prey

[32]P label

Dscam1 
Dscam1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dscam1 
Elav-binding site
sufficient binding region
UUUUUAAUUGAUUACGUUCGCUUUUGUUUGAUUAUUGUUUUGG
Dscam1 
Elav-binding site
mutation disrupting interaction
UGUGUAAGUGAGUACGGUCGCUGUGGUGUGAUGAUGGGUGUGG
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey commercially synthesized.

(Zhang et al., 2019)
FBrf0246833-4.CLIP.SEQ
Reference
Carrasco et al., 2020
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
elav 

ELAV

bait
Dscam1 

Dscam1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads; bait produced from endogenous gene; prey produced from endogenous gene.

(Carrasco et al., 2020)
External Crossreferences and Linkouts ( 0 )
References (2)