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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000120193
Interaction Network
Interactions Browser links
PRL-1 network
uex network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0243653-1.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

PRL-1

bait

HA tag

uex 

Uex

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

FBrf0243653-2.PD.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

PRL-1

bait

biotin tag

uex 

Uex

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
interaction domain residues 77,109
mutation decreasing interaction
aa 77,109

D77A,C109S

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was lysate of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

FBrf0243653-3.PD.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

PRL-1

bait

GST tag

uex 

Uex

prey
uex 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
uex 
CBS domain
mutation decreasing interaction
aa 485-486

E485,G486 converted to D, coordinates relative to uex-PE

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait source unspecified; prey derived from mutant extract.

External Crossreferences and Linkouts ( 0 )
References (1)