FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000120307
Interaction Network
Interactions Browser links
Prx2 network
Mekk1 network
Reported Interactions
FBrf0244286-1.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Prx2 

Jafrac1

bait

SBP tag

Mekk1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

Under non-reducing conditions, multiple Mekk1-containing species co-precipitate with Jafrac1 while under reducing conditions only monomeric Mekk1 co-precipitates suggesting both covalent and non-covalent interactions.

FBrf0244286-2.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Mekk1

bait

SBP tag

Prx2 

Jafrac1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Under non-reducing conditions, multiple Jafrac1-containing species co-precipitate with Mekk1.

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

External Crossreferences and Linkouts ( 0 )
References (1)