FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000120724
Interaction Network
Interactions Browser links
cher network
zip network
Reported Interactions
FBrf0221311-1.coIP.WB
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note
cher 

Cher

bait
zip 

Zip

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The interaction of cher with zip is increased in tissues with activated Ras85D and disrupted epithelial polarity (scrib mutant background).

Source was larval eye-antennal disc of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

FBrf0254246-1.coIP.MS
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note
cher 

Cher

bait
zip 

Zip

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval eye-antennal discs of an epithelial tumour model fly line; bait produced from endogenous gene; prey produced from endogenous gene.

cher interacted with zip in an Ras85D-v12 - scrib mutant tumour model fly line in combination with an cher mutant which only expresses the smaller cher-90 isoform.

FBrf0254246-4.coIP.WB
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note
cher 

Cher

bait
zip 

Zip

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

cher interacted with zip in an Ras85D-v12 - scrib mutant tumour model fly line.

Source was larval eye-antennal discs of an epithelial tumour model fly line; bait produced from endogenous gene; prey produced from endogenous gene.

External Crossreferences and Linkouts ( 0 )
References (2)