FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
sd, sna
FlyBase ID
FBig0000121656
Interaction Network
Interactions Browser links
sd network
sna network
Reported Interactions
FBrf0252889-1.coIP.WB
Reference
Ding et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
sd 

Sd

bait

HA tag

sd 
sna 

Sna

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
sd 
N terminal domain
sufficient binding region
aa 1-213
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ding et al., 2022)
FBrf0252889-2.coIP.WB
Reference
Ding et al., 2022
Description
physical association
Assay
Collection
Source/Stage
wing disc / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sd 

Sd

bait

HA tag

sna 

Sna

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval wing discs of transgenic fly line; bait produced from tagged transgenic construct; prey produced from transgenic construct.

(Ding et al., 2022)
FBrf0252889-3.PD.WB
Reference
Ding et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sna 

Sna

bait

GST tag

sd 

Sd

prey

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as recombinant fusion proteins in bacterial system.

(Ding et al., 2022)
External Crossreferences and Linkouts ( 0 )
References (1)