FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Sting
FlyBase ID
FBig0000123545
Interaction Network
Interactions Browser links
Sting network
Reported Interactions
FBrf0260102-1.CM.WB
Reference
Wang et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Sting 

STING

self
Sting 

STING

self
Sting 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Sting 
cryptic RIP homotypic interaction (cRHIM1) motif
mutation decreasing interaction
aa 188-191

VTFG deletion; coordinates relative to Sting-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

cGAMP intensifies wild-type Sting oligomerization. cRHIM1 motif deletion has reduced oligomerization and is not amplified by cGAMP.

(Wang et al., 2024)

Source was S2 cell line; protein produced from transfected construct.

(Wang et al., 2024)
External Crossreferences and Linkouts ( 0 )
References (1)