FB2026_02 , released June 18, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
TBC1d7, Tsc1
FlyBase ID
FBig0000123807
Interaction Network
Interactions Browser links
TBC1d7 network
Tsc1 network
Reported Interactions
FBrf0216604-28.coIP.MS
Reference
Glatter et al., 2011
Description
physical association
Assay
Collection
PPI_InR-Tor
Source/Stage
Cell line used
Kc167
Participants
Corresponds to
Reported as
Role
Note
Tsc1 

Tsc1

bait

GFP tag

TBC1d7 

CG6182

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

SAINT score = 1

(Glatter et al., 2011)

Source was cell extract of Kc167 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Glatter et al., 2011)
FBrf0238110-1.coIP.WB
Reference
Ren et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
TBC1d7 

dTBC1D7

bait

FLAG tag

TBC1d7 
Tsc1 

TSC1

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TBC1d7 
interaction domain residue 125
necessary binding region
aa 125

I125Q coordinates relative to TBC1d7-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ren et al., 2018)
FBrf0238110-2.coIP.WB
Reference
Ren et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Tsc1 

TSC1

bait

HA tag

TBC1d7 

dTBC1D7

prey

FLAG tag

TBC1d7 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TBC1d7 
interaction domain residue 125
necessary binding region
aa 125

I125Q coordinates relative to TBC1d7-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ren et al., 2018)
External Crossreferences and Linkouts ( 0 )
References (2)