report comment: FRT-deleted (active) form of Act5C-PKA carried on descendant transposon P{PKA.mC.Act5C}.Once the FRT cassette is removed, the mouse PKA allele carried in this construct is constitutively active (reduced binding to regulatory subunit). PKA coding sequence terminates with human growth hormone polyA signal.
report comment: FRT-deleted (active) form of Act5C-PKA carried on descendant transposon P{PKA.mC.Act5C}.Once the FRT cassette is removed, the mouse PKA allele carried in this construct is constitutively active (reduced binding to regulatory subunit). PKA coding sequence terminates with human growth hormone polyA signal.