Kemphues, K.J., Raff, E.C., Kaufman, T.C. (1983). Genetic analysis of B2t, the structural gene for a testis-specific -tubulin subunit in Drosophila melanogaster. Genetics 105(): 345--356.
FlyBase ID
FBrf0039448
Publication Type
Research paper
Abstract
Genetic analysis of the B2t locus has resulted in the recovery of four recessive mutations in the B2t structural gene and a deficiency that deletes the locus. Two of the mutations were recovered as suppressors of B2tD, a dominant male sterile mutation at the locus, and two were induced on wild-type chromosomes. All four mutant genes encode beta 2-tubulin subunits that are synthesized at normal rates but do not accumulate. All mutants are completely male sterile as homozygotes.
