Totskii, V.N., Khaustova, N.D., Andrievskii, A.M., Gandiruk, N.G., Belova, G.I., Eserkepova, E.V. (1990). Ekspressivnost' gen-enzimnykh sistem i pokazateli zhiznesposobnosti v ontogeneze inbrednykh linii i gibridov drozofily. [Expressivity of gene-enzyme systems and the viability indexes in ontogenesis of inbred lines and of Drosophila hybrids.]  Genetika, Moscow 26(10): 1791--1799.

FBrf0052020

Research paper

The activity, physico-chemical properties and multiple molecular forms of enzymes (alcohol dehydrogenase, superoxide dismutase, nonspecific alpha- and beta-esterases, hydroxide peptidohydrolase) were studied in ontogenesis of Drosophila inbred lines and their hybrids under conditions of high temperature (37-41 degrees C) and the presence in food of 10% ethanol. It was established that resistance of individuals to the effect of high temperature and alcohol, including manifestation of adaptive heterosis in hybrids not always depends on the level of the activity of enzymes analysed and is rather determined by allelic state of the appropriate structural genes. So, in conditions of the alcohol stress the individuals containing highly active F form of alcohol dehydrogenase have selective advantage and flie with hybrid F/S enzyme of higher activity and heat stability are more stable to the effect of high temperature. It is supposed that the complexes of adaptation genes (CGA) are formed in individuals of populations in response to the regular action of unfavourable environmental factors. These complexes condition optimal allelic control and most efficient regulation of enzyme activity in environment. Genotypic adaptation of individuals as well as occurrence of adaptive heterosis in hybrids seem likely to be connected with formation of CGA.