Evgen'ev, M.B., Denisenko, O.N. (1990). Vliianie ts-mutatsii na ekspressiiu genov, indutsiruemykh teplovym shokom u Drosophila melanogaster. [The effect of ts-mutation on expression of genes induced by heat shock in Drosophila melanogaster.] III. Sintez belkov, rodstvennykh BShT70. [Synthesis of proteins cognate to HSP70.] Genetika, Moscow 26: 266--271.

FBrf0052033

Research paper

2D-electrophoresis performed as described by O'-Farrel has revealed clear-cut differences in the pattern of proteins synthesized in the cells of wild-type flies and in the cells of ts-lethal. The cells of the mutant studied after heat-shock exhibit not only the lack of HSP83 and HSP35 but also the absence of a few of the heat-shock proteins belonging to the HSP70 group. Moreover, in the cells of the mutant an intensive synthesis of a protein with mol. weight 72 KDa was observed after heat-shock. This protein belongs to highly abundant heat-shock cognate proteins (HSCP) which are usually not induced by temperature elevation.