Mamon, L.A., Kutskova, Y.A. (1993). [The role of the heat-shock proteins in recovery of cell proliferation following high temperature treatment of Drosophila melanogaster.]  Genetika, Moscow 29(5): 791--798.

FBrf0058627

Research paper

The processes of the recovery of proliferation activity of nervous ganglion cells following heat-shock (37 degrees C, 30 min) were compared in two strains of Drosophila melanogaster (Canton S--the wild-type strain and 1(1)ts403--the mutant with the defect in the heat-shock protein system). The ts-mutant is characterized by the delay n reaching the maximum level in the HSP's synthesis and by more prolonged synthesis of these proteins after heat shock as compared with the wild-type strain. The block in cell proliferation after heat-shock is also more prolonged in the ts mutant's nervous ganglion in comparison with the wild-type strain. These results are n accordance with the hypothesis about the role of HSP's in cell proliferation.