Subject: Re: prp33/innexins
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Subject: Re: prp33/innexins
Dear Chihiro, Kathy Curtin and I have put our heads together about the
naming of the innexins and this is the schemethat we have come up with:
Name			Synonym			Orthologue
Ogre			Dm-inx1			Sa-inx(1)
Dm-inx2			prp33			Sa-inx(2)
Dm-inx3 (Stebbings et al, submitted to J. Cell Biol.)
Dm-inx6			prp6
Dm-inx7			prp7
I know this leaves us minus Dm-inx 4 & 5 but I imagine the gap will soon be
filled.
I have enclosed a copy of my correspondence with Kathy, but please get in
touch with her if you require independent confirmation.
Best Wishes
Jane Davies
Subject: Re: innexins
Status:
Jane:
	This sounds fine and good to me. Tell Flybase to go ahead.
Thanks,
Kathy
On Wed, 22 Sep 1999, Jane Davies wrote:
> >Dear Jane:
> >
> >	I have no real objection to renaming prp33 since the name is
> >somewhat meaningless. But we should also then rename the two other prp
> >genes 6 and 7. Does that sound reasonable? Then if someone finds an
> >orthlogue in another speices they can follow the Drosophila nomenclature.
> >Though I wonder how easy it will be to idntify orthologues with certainty
> >when many family members remain unidentified. But perhaps we have to name
> >as we go. I will talk to Bob about the other prp genes and write to the
> >fellow at Flybase. We did agree to the innexin name if somewhat
> >reluctantly.
> >
> >Kathy
> >
> >Dear Kathy
>
> Thanks for your prompt reply. I think that the best thing is to re-name all
> the 'prp' genes if you and Bob agree, but have 'prp' as a synonym. I
> realise that it is often difficult to identify orthologues but, as you say,
> the best thing is just to name as we go and fine-tune the system as
> necessary.
>
> This is my suggested scheme:
>
> Name			Synonym			Orthologue
>
> Ogre			Dm-inx1			Sa-inx(1)
> Dm-inx2			prp33			Sa-inx(2)
> Dm-inx3 (Stebbings et al, submitted to J. Cell Biol.)
> Dm-inx6			prp6
> Dm-inx7			prp7
>
> I know this leaves us minus Dm-inx 4 & 5 but I imagine the gap will soon be
> filled. If you think this system is OK, I'll forward this email to Flybase
> and to Jocelyn Shaw.
>
> Best Wishes
>
> Jane Davies
>
>
Dr Jane Davies
Sussex Centre for Neuroscience
Sussex University
Falmer
Brighton BN1 9QG
UK
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>Dear Jane and Kathryn,
>
>I'm glad to see that you've managed to come to an agreement. There is
>one point however, FlyBase has a policy of assuming that all genes in
>its database are Drosophila genes and thus drops any 'D' or 'Dm'
>suffixes as being superfluous. So the gene names in FlyBase will  be:- 
>
>Name			Synonym			Orthologue
>
>Ogre			Dm-inx1			Sa-inx(1)
>inx2			prp33			Sa-inx(2)
>inx3 	(Stebbings et al, submitted to J. Cell Biol.)
>inx6			prp6
>inx7			prp7
>
>Obviously when referring to these genes in the context of the whole
>family of genes, the 'Dm' prefix is necessary, but FlyBase does not
>consider it to be part of the gene name.
>
>I hope this doesn't cause any problems.
>
>Best wishes,
>
>Chihiro.
>
Dear Chihiro
That's fine!
Jane
Dr Jane Davies
Sussex Centre for Neuroscience
Sussex University
Falmer
Brighton BN1 9QG
UK