Subject: Helping FlyBase: ADRC-60, 311A and 632A
Dear Doug,
We are currently curating the abstracts for the upcoming 41st
(Pittsburgh) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstracts:
'PERK, a newly discovered eIF-2 alpha kinase is a ER
transmembrane protein.'
'ER stress induces phosphorylation of eIF-2 alpha,
repression of protein synthesis, and induction of ER chaperone genes.'
and
'Signal transduction pathway mediating the endoplasmic
reticulum unfolded protein response: IRE1 and the ER chaperones.'
You mention two genes that are new to FlyBase, Perk and Ire.
Do you have a map locations for Perk and Ire? This is a data class we
like to track, if possible.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-60, 311A and 632A
Rachel,
PERK is located at 83A1-3; Reference, Unpublished Zhang, P. and Cavener, D.R.
IRE1 is located at 92B1-B7; Reference unpublished Geething, N. and
Cavener, D.R.
We should be submitting sequence/transcript mapping data to Genbank shortly.
Cheers, Doug
Douglas R. Cavener
Department of Molecular Biology
Box 1820 Station B
Vanderbilt University
Nashville, TN 37235