protein kinase, endonuclease, a regulator of the unfolded protein response, leading to the activation of the transcription factor Xbp1 - regulated Ire1-dependent decay - regulation of RNA splicing - photoreceptor differentiation and rhabdomere morphogenesis
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ire1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ire1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Changes in expression profiles associated with the unfolded protein response have been analyzed in S2 cells following treatment with dsRNA made from templates generated with primers directed against this gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.