eye, with Scer\GAL4GMR.long
eye, with Scer\GAL4GMR.PU
The expression of Ire1UAS.Tag:V5 under the control of Scer\GAL4GMR.long leads to large anomalies to the external eyes; scanning electron microscopy analysis reveals a glassy eye surface characterized by ommatidial disruption, with severe loss of photoreceptors, and loss of interommatidial bristles; transmission electron microscopy analysis reveals a severe increase in the number of autophagosomes per ommatidium encircling mitochondria compared to controls, as well as amorphous structures which appear to be the partially degraded cellular debris.
In the eye disc, there is elevated apoptosis and increased numbers of autophagosomes/autolysosomes and decreased autophagic flux, as compared to controls.
Adults expressing Ire1UAS.Tag:V5 under the control of Scer\GAL4Ddc.PU show age-dependent impairment in climbing ability, associated with a progressive decrease in PPM1/2 and PPM3 neurons, despite of no significant changes in other DA neurons (PAL, PPL1 and PPL2 clusters) as compared to controls.
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, enhanceable by Xbp1KK102632, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, enhanceable by Xbp1JF02012, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, suppressible | partially by Atg6GD11647, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, suppressible | partially by Atg6GD11647, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | adult stage phenotype, suppressible | partially by Atg13G6421/Atg13G6421
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | adult stage phenotype, suppressible | partially by Atg600096/Atg600096
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has increased cell death | somatic clone | larval stage phenotype, suppressible | partially by Atg13G6421/Atg13G6421
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has increased cell death | somatic clone | larval stage phenotype, suppressible | partially by Atg600096/Atg600096
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | larval stage phenotype, suppressible by bskDN.UAS, Atg13G6421/Atg13G6421
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | larval stage phenotype, suppressible by bskDN.UAS, Atg600096/Atg600096
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | larval stage phenotype, suppressible | partially by BacA\p35UAS.cHa, Scer\GAL4Act.PU
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | larval stage phenotype, suppressible | partially by bskDN.UAS, Scer\GAL4Act.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, suppressible by Atg5KK108904, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, suppressible by Atg5KK108904, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, suppressible by Atg12GD15230, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, suppressible by Atg12GD15230, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, suppressible by Atg13HMS02028, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, suppressible by Atg13HMS02028, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, suppressible by Atg14HMS02025, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, suppressible by Atg14HMS02025, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, suppressible | partially by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, suppressible by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has decreased cell number | adult stage phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has decreased cell number | adult stage phenotype, suppressible by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, non-suppressible by Atg1HMS06014, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, non-suppressible by Atg1HMS06014, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has visible | adult stage phenotype, non-suppressible by Atg8aHMJ22416, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has decreased size | adult stage phenotype, non-suppressible by Atg8aHMJ22416, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by BacA\p35UAS.cHa, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg1GD7149, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg10KK108980, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg12HMS01153, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg12JF02704, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg13GD12202, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg16GD10140, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg16HMS01347, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg17KK101847, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg18aJF02898, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg101KK101226, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by DroncDN.UAS.cUa, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg4aJF03003, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by DroncI29/DroncI29
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, non-suppressible by Xbp1KK102632, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has increased cell death | third instar larval stage phenotype, non-suppressible by Xbp1JF02012, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg4aMB03551, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg5KK108904, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg6JF02897, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg8aGD4654, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg8aKK102155, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg9JF02891, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has visible | adult stage phenotype, non-suppressible by Atg9HMS01246, Scer\GAL4GMR.long
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of increased cell death | larval stage | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of decreased cell number | larval stage | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of increased cell death | adult stage | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5, Scer\GAL4Act.PU is an enhancer of decreased cell number | larval stage | somatic clone phenotype of Rab5S43N.UAS, Scer\GAL4Act.PU
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of decreased size | adult stage phenotype of Scer\GAL4GMR.PU, egrUAS.cIa
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of visible | adult stage phenotype of Scer\GAL4GMR.PU, egrUAS.cIa
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is a suppressor | partially of melanotic necrosis | somatic clone | adult stage phenotype of scrib1
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has increased cell death | somatic clone | larval stage phenotype
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has decreased cell number | somatic clone | larval stage phenotype
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, enhanceable by Xbp1KK102632, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, enhanceable by Xbp1KK102632, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, enhanceable by Xbp1JF02012, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, enhanceable by Xbp1JF02012, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible | partially by BacA\p35UAS.cHa, Scer\GAL4Act.PU
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible | partially by bskDN.UAS, Scer\GAL4Act.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, suppressible by Atg5KK108904, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, suppressible by Atg12GD15230, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, suppressible by Atg13HMS02028, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, suppressible by Atg14HMS02025, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, suppressible | partially by Atg6GD11647, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible | partially by Atg13G6421/Atg13G6421
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible | partially by Atg600096/Atg600096
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible by bskDN.UAS, Atg13G6421/Atg13G6421
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype, suppressible by bskDN.UAS, Atg600096/Atg600096
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, suppressible | partially by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has interommatidial bristle phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has interommatidial bristle phenotype, suppressible | partially by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, suppressible | partially by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, suppressible by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye photoreceptor cell phenotype, suppressible by Atg8bJF02706, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye photoreceptor cell phenotype, suppressible by Atg7GD11671, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has interommatidial bristle phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, suppressible | partially by Xbp1UAS.s.Tag:V5, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has ommatidium phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has interommatidial bristle phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, suppressible | partially by bskGD10555, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has autophagosome | increased number | somatic clone | larval stage phenotype, non-suppressible by Xbp1GD4745, Scer\GAL4Act.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, non-suppressible by Atg1HMS06014, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.PU has eye phenotype, non-suppressible by Atg8aHMJ22416, Scer\GAL4GMR.PU
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg1GD7149, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg4aJF03003, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg4aMB03551, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg5KK108904, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg6JF02897, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg8aGD4654, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg8aKK102155, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg9JF02891, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg9HMS01246, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg10KK108980, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg12HMS01153, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg12JF02704, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg13GD12202, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg16GD10140, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg16HMS01347, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg17KK101847, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg18aJF02898, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by Atg101KK101226, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by DroncDN.UAS.cUa, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by DroncI29/DroncI29
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, non-suppressible by Xbp1JF02012, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye disc phenotype, non-suppressible by Xbp1KK102632, Scer\GAL4GMR.long
Ire1UAS.Tag:V5, Scer\GAL4GMR.long has eye phenotype, non-suppressible by BacA\p35UAS.cHa, Scer\GAL4GMR.long
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of eye phenotype of Scer\GAL4GMR.PU, egrUAS.cIa
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of eye-antennal disc | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is an enhancer of autophagosome | larval stage | increased number | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5, Scer\GAL4Act.PU is an enhancer of eye-antennal disc | somatic clone phenotype of Rab5S43N.UAS, Scer\GAL4Act.PU
Ire1UAS.Tag:V5/Scer\GAL4Act.PU is a suppressor | partially of eye | somatic clone phenotype of scrib1
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has eye-antennal disc | somatic clone phenotype
Ire1UAS.Tag:V5, Scer\GAL4Act.PU, scrib1 has autophagosome | increased number | somatic clone | larval stage phenotype
Ire1UAS.Tag:V5 is rescued by Scer\GAL4GMR.long/Ire1GD3071
Ire1UAS.Tag:V5 is rescued by Ire1HMS03003/Scer\GAL4GMR.long