FlyBase Allele Report: Dmel\Atg8a[HMJ22416]

General Information

Symbol

Dmel\Atg8a^HMJ22416

Species

D. melanogaster

Name

FlyBase ID

FBal0300771

Feature type

allele

Associated gene

Dmel\Atg8a

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ22416}

Also Known As

UAS-Atg8a^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ22416}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ22416

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal starvation stress response | adult stage, with Scer\GAL4^repo

(Leung et al., 2024)

decreased cell number | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

increased mortality, with Scer\GAL4^repo

(Leung et al., 2024)

Phenotype Manifest In

female germline stem cell | decreased number, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Atg8a^HMJ22416, Scer\GAL4^{VP16.nanos.UTR} is a non-enhancer of decreased cell number | oogenesis phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

NOT Suppressor of

Statement

Reference

Atg8a^HMJ22416, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.PU

(Zheng et al., 2023)

Atg8a^HMJ22416, Scer\GAL4^GMR.PU is a non-suppressor of decreased size | adult stage phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.PU

(Zheng et al., 2023)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Atg8a^HMJ22416, Scer\GAL4^{VP16.nanos.UTR} is a non-enhancer of female germline stem cell | decreased number phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Atg8a^HMJ22416, Scer\GAL4^{VP16.nanos.UTR} is a non-enhancer of female fusome phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Atg8a^HMJ22416, Scer\GAL4^{VP16.nanos.UTR} is a non-enhancer of female germline cyst phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

NOT Suppressor of

Statement

Reference

Atg8a^HMJ22416, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Ire1^UAS.Tag:V5, Scer\GAL4^GMR.PU

(Zheng et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

58309

y¹ v¹; P{TRiP.HMJ22416}attP40

NIG-Fly

HMJ22416

y¹ v¹; P{TRiP.HMJ22416}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Atg8a^HMJ22416

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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