Subject: Re: gammy legs Dear Rachel, Please consider the attachment a personal communication for now. We have submitted a manuscript and well let you know when it is in press. Please let me know if there is any other information you require. Regards, Ken ===================================================================== Previously known as BEST:LD21971 Gene: gam Symbol: gam Full name: gammy legs D. melanogaster gene gammy legs, abbreviated as gam, is reported here. It encodes a PHD- finger protein, which is localized to the nucleus. It is ubiquitously expressed at low levels in the embryo and imaginal discs. Similar sequences have been identified in Homo sapiens. It has been sequenced and its amino acid sequence is also avaliable. It has been mapped cytologically to 100C7--D. It interacts genetically with arm, dsh and axin, and acts genetically as a positive regulator of Wingless signaling. Null mutations have been isolated that affect the epidermis, denticle belts, antenna, legs and wings and are recessive viable. There is one recorded mutant allele, but it is not available from the public stock centers. gammy legs is discussed in 5 references, dated between 1999 and 2001. These include at least 2 molecular studies. GENE PRODUCT Biological process: Wingless signaling pathway Rep. Protein sequence: 815 aa, 2000 (full cDNA sequence submitted to genbank) Protein domains: PHD-finger domain GENOMIC ORGANISATION Genomic sequence analysis: full cDNA sequence submitted to Genbank Cytogenic map: 100C6-7 Rep DNA sequence: Genebank accession number AY075095 ===================================================================== > Dear Ken, > >> I would like to update the information on the gammy legs gene > > brilliant! If the information about gammy legs is soon to be published > then just let us know where and we will look out for it. However if > you want to tell us things that will not be due for publication soon > then just send us an email (to flybase-updates is > fine or to me direct) and we will curate it as a personal communication > to FlyBase from you. Don't worry about the format or content \- we can > go back and forth if necessary until we are all happy with the text. > > Best regards, > > Rachel. > for the FlyBase consortium.
