Hirota, Y., Sawamoto, K., Okano, H. (2002). tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila.  Mech. Dev. 119(Suppl. 1): S279--S283.

FBrf0161470

Research paper

We cloned and characterized the Drosophila gene, tincar (tinc), which encodes a novel protein with eight putative transmembrane domains. The tinc mRNA was expressed specifically in four of the six pairs of cardioblasts in each segment, in a pattern identical to that of tinman (tin), a homeobox gene required for the specification of the dorsal vessel. In the non-Tin-expressing pairs of cardioblasts, tinc transcription seemed to be repressed by Seven-up.