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General Information
Symbol
Dmel\svpUAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Kramer
FlyBase ID
FBal0044362
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-svp1, UAS-svp
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a cDNA that encodes the svp type 1 isoform.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Larvae expressing svpScer\UAS.cKa under the control of Scer\GAL4so-7.GAL4 show no change in the overall number of photoreceptors in the Bolwig's organ.

Early born cells in the NB7-1 and NB7-3 lineages are missing from 30-40% of abdominal hemisegments in svpScer\UAS.cKa; Scer\GAL4en-e16E embryos at stage 15. In 16% of hemisegments in these embryos, the entire NB 7-3 lineage is missing. In contrast, normal numbers of cells in both of these lineages develop in svpScer\UAS.cKa; Scer\GAL4elav-C155 embryos.

Expression of svpScer\UAS.cKa under the control of Scer\GAL4pnr-MD237 results in dorsal closure defects.

When svpScer\UAS.cKa is driven by Scer\GAL4Act5C.PI, Scer\GAL4elav.PLu, or Scer\GAL4Alk.6.5 adults are viable and fertile. When driven by Scer\GAL4dpp.blk1, adults are also viable and fertile with no detectable defects. When svpScer\UAS.cKa is driven by Scer\GAL4Dll-md23 animals die as embryos. When driven by Scer\GAL4h-1J3 animals die as first instar larvae. When svpScer\UAS.cKa is driven by Scer\GAL4GMR.PF, animals are viable and fertile but have rough eyes, with moderate ommatidial disorganisation.

All of the ommatidia in flies expressing svpScer\UAS.cKa under the control of Scer\GAL4sca-537.4 lack R7 and R8 photoreceptor cells.

svpScer\UAS.cKa/Scer\GAL4sca-T3 individuals die as embryos or larvae. Adult escapers show mild roughening of the eye due to lack of photoreceptor R7.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Additional Comments
Genetic Interactions
Statement
Reference

The formation of R7 cells is rescued in flies expressing svpScer\UAS.cKa under the control of Scer\GAL4sca-537.4 by expression of Ras85DV12.sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
svpScer\UAS.cKa
svpUAS.cKa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Kramer
Secondary FlyBase IDs
    References (16)