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Citation
Yang, C.H., Belawat, P., Hafen, E., Jan, L.Y., Jan, Y.N. (2008). Drosophila egg-laying site selection as a system to study simple decision-making processes.  Science 319(5870): 1679--1683.
FlyBase ID
FBrf0204415
Publication Type
Research paper
Abstract

The ability to select a better option from multiple acceptable ones is important for animals to optimize their resources. The mechanisms that underlie such decision-making processes are not well understood. We found that selection of egg-laying site in Drosophila melanogaster is a suitable system to probe the neural circuit that governs simple decision-making processes. First, Drosophila females pursue active probing of the environment before depositing each egg, apparently to evaluate site quality for every egg. Second, Drosophila females can either accept or reject a sucrose-containing medium, depending on the context. Last, communication of the "acceptability" of the sucrose-containing medium as an egg-laying option to the reproductive system depends on the function of a group of insulin-like peptide 7 (ILP7)-producing neurons. These findings suggest that selection of egg-laying site involves a simple decision-making process and provide an entry point toward a systematic dissection of this process.

PubMed ID
PubMed Central ID
PMC2581776 (PMC) (EuropePMC)
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075
    Data From Reference
    Alleles (6)
    Genes (6)
    Natural transposons (1)
    Experimental Tools (3)
    Transgenic Constructs (6)
    Transcripts (2)