Bradu, A., Ma, L., Bloor, J.W., Podoleanu, A. (2009). Dual optical coherence tomography/fluorescence microscopy for monitoring of Drosophila melanogaster larval heart. J. Biophotonics 2(6-7): 380--388.
FlyBase ID
FBrf0208384
Publication Type
Research paper
Abstract
This article demonstrates a combined instrument of two imaging modalities to acquire information on cardiac function in larval Drosophila melanogaster: optical coherence tomography (OCT) and laser scanning fluorescence microscopy (LSFM). For this purpose, a dedicated imaging instrument able to sequentially provide cross-sectional OCT and C-scan LSFM images has been developed. With this dual-imaging system, the heart can be easily located and visualized within the specimen and the change of the heart shape in a cardiac cycle can be monitored.
