FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Citation
Sundararajan, L., Miller, D.M. (2018). Neuronal Fat and Dendrite Morphogenesis: The Goldilocks Effect.  Trends Neurosci. 41(5): 250--252.
FlyBase ID
FBrf0238769
Publication Type
Review
Abstract
Two recent studies by Meltzer et al. and Ziegler et al. use Drosophila larvae to demonstrate that cell-autonomous regulation of lipid biosynthesis defines the complexity and function of highly branched nociceptive neurons. Their findings show that lipid biosynthesis in the neuron is fine-tuned for optimal dendrite morphology and sensitivity.
PubMed ID
29548516
PubMed Central ID
PMC5924613 (PMC) (EuropePMC)
DOI
10.1016/j.tins.2018.02.011
Related Publication(s)
Research paper

Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons.
Meltzer et al., 2017, Cell Rep. 21(4): 859--866 [FBrf0237004]

Cell-Autonomous Control of Neuronal Dendrite Expansion via the Fatty Acid Synthesis Regulator SREBP.
Ziegler et al., 2017, Cell Rep. 21(12): 3346--3353 [FBrf0237511]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Neurosci.
    Title
    Trends in Neurosciences
    Publication Year
    1978-
    ISBN/ISSN
    0166-2236
    Data From Reference
    Genes (2)
    Human Disease Models (2)