FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Citation
Maggert, K., Kindelay, S. (2025). The Drosophila FM7-A Strain Contains a Fixed Translocation Involving the X and 4 Chromosomes.  MicroPubl Biol 2025(): .
FlyBase ID
FBrf0262931
Publication Type
Research paper
Abstract
We discovered that a commonly used balancer chromosome - FM7-A, Tb [1] - exists as an uncharacterized translocation between the progenitor FM7a chromosome and a normal chromosome 4 . Genetic and cytological data evidence show that T (1 ; 4) FM7-A translocates about 5% of chromosome 1 material to an entire chromosome 4 , thus the large "chromosome 1 " segregant is lethal without the small "chromosome 4 " segregant, though the latter is viable and fertile without the former. We characterize this balancer chromosome to inform Drosophila molecular-geneticists of the structure as it may affect their use of this balancer chromosome and the interpretations of their results.
PubMed ID
PubMed Central ID
PMC12272177 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    MicroPubl Biol
    Title
    microPublication Biology
    ISBN/ISSN
    2578-9430
    Data From Reference
    Aberrations (7)
    Balancers (2)
    Genes (8)
    Insertions (1)