iRFP713 is a dimeric infra-red fluorescent protein with an excitation peak of 690nm and an emission peak of 713nm in vitro. It is an artificial derivative of the bacteriophytochrome encoded by the Rhodopseudomonas palustris RpBphP2 gene. In order to fluoresce, iRFP713 requires a biliverdin (linear tetrapyrrole) cofactor to act as the chromophore. This can be supplied in a transgenic animal by including a transgenic construct that encodes a heme oxygenase (HO) (PMID:21765402, PMID:23770755).