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General Information
Symbol
Voltron
FlyBase ID
FBto0000488
Name
Description
Description

Voltron is a chemigenetic voltage sensor. It consists of a rhodopsin from Acetabularia acetabulum, mutated to carry a D81N amino acid substitution which inactivates the proton pump, fused to a Halo-tag which can covalently bind a fluorophore dye ligand such as JF[[525]]. Changes in membrane potential result in a change in the level of fluorescence resonance energy transfer (FRET) quenching of the fluorophore dye by the rhodopsin; depolarization results in decreased fluorescence (PMID:31371562).

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Transgenic Constructs
Encodes tool (2)
Insertions ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Voltron
Name Synonyms
Secondary FlyBase IDs
    References (3)