Pleckstrin homology domain of the Homo sapiens AKT serine/threonine kinase 1 (AKT1) gene (HGNC:391). This domain can bind specifically to particular classes of phosphatidylinositol. This domain can thus be used to monitor the distribution of these phosphatidylinositols within a cell, if fused to an appropriate reporter protein, or to target a tagged protein to a particular subcellular localization via phosphatidylinositol binding.