FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{lab(-6.3)-lacZ}
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General Information
Symbol
P{lab(-6.3)-lacZ}
FlyBase ID
FBtp0004402
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
lacZ reporter
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele Ecol\lacZlab.-6.3
Transgenic product class
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Description

Expression of lacZ driven by a 6.3kb fragment extending in the 5' direction from a SacII site at base pair 325 of lab.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

EcollacZ reporter gene expression isobserved from embryonic stage 13. The pattern closely resembles labexpression in a thin stripe of cells in the midgut epithelium thatcoextends approximately with Ubx expression in parasegment 7 of theadhering visceral mesoderm. The stripe widens and displays a gradedpattern with the strongest expression posteriorly. As with labexpression, a 2-3 cell wide gap is present between the posterior boundaryof EcollacZ expression and the second midgut constriction. In lab mutants,midgut expression is eliminated prior to stage 15 and occurs at low levelsthereafter. Expression is completely eliminated in dpp mutant embryos.Ectopic expression is seen posteriorly in an abd-A mutants andanteriorly in a Pc mutant. Expression is reduced in a wg mutant and isderepressed posteriorly.

 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
7.31 lab-lacZ
CZ 7.11 lab-lacZ
P{lab(-6.3)-lacZ}
Secondary FlyBase IDs
    References (11)