FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-htl.λ.K443A}
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General Information
Symbol
P{UAS-htl.λ.K443A}
FlyBase ID
FBtp0019870
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele htlK443A.λ.UAS.Tag:HA
Transgenic product class
Component
Use(s)
Encoded product / tool
Description

UAS regulatory sequences drive expression of a kinase-dead form of "activated" htl, which consists of the transmembrane and cytoplasmic domains of htl carrying the K443A mutation to abolish kinase function, the dimerization domain of the bacteriophage λ cI repressor (included to induce constitutive dimerization of the encoded protein) and two copies of the Tag:HA tag.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-htl.λ.K443A}
pUAST-.λ.K443A-2xHA
Secondary FlyBase IDs
    References (3)