FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hpo.Δauto}
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General Information
Symbol
P{UAS-hpo.Δauto}
FlyBase ID
FBtp0020663
Feature type
transgenic_transposable_element
Component Allele(s)
hpoΔauto.UAS
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele hpoΔauto.UAS
Transgenic product class
gain_of_function_variant
(Udan et al., 2003)
inframe_deletion
(Udan et al., 2003)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
hpo
Description

UASt regulatory sequences drive expression of a hyperactive form of hpo that carries a deletion which removes the autoregulatory domain (amino acid residues 355-465 are missing). This deletion is analogous to a deletion in human MST1 that causes an increase in kinase activity in vitro.

(Udan et al., 2003)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-hpo.Δauto}
UAS hpoΔINH (Δauto)
(Kango-Singh, 2012.10.31)
UASHpo
(Verghese et al., 2012)
Secondary FlyBase IDs
    References (4)