FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Recombinant Construct: P{GD12574}
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General Information
Symbol
P{GD12574}
FlyBase ID
FBtp0025904
Feature type
transgenic_transposable_element
Component Allele(s)
HemK2GD12574
SnapinGD12574
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele SnapinGD12574
Transgenic product class
RNAi_reagent
(Dickman et al., 2012)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD12574
Description

UASt regulatory sequences drive expression of an RNAi construct which targets sequence encoding the CG9960 open reading frame (ORF). This ORF is part of a dicistronic transcript that encodes both Snapin and CG9960, and expression of both these genes is down-regulated by this RNAi construct.

(Dickman et al., 2012)
Component allele HemK2GD12574
Transgenic product class
RNAi_reagent
(Dickman et al., 2012)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD12574
Description

UASt regulatory sequences drive expression of an RNAi construct which targets sequence encoding the CG9960 open reading frame (ORF). This ORF is part of a dicistronic transcript that encodes both Snapin and CG9960, and expression of both these genes is down-regulated by this RNAi construct.

(Dickman et al., 2012)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments

Possible off-target effects (low probability).

(Dickson et al., 2007.7.18)

Targets multiple paralogous genes.

(Dickson et al., 2007.7.18)

Expression under the control of Scer\GAL4pnr-MD237 results in viable flies.

(Mummery-Widmer et al., 2009)

Expression of P{GD12574} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies.

(Neely et al., 2010)

Adults expressing P{GD12574} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression of P{GD12574} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in viable flies.

(Neely et al., 2010)

Expression under the control of Scer\GAL4Mef2.PR results in viable flies.

(Schnorrer et al., 2010)
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
VDRC
v28145
w1118; P{GD12574}v28145
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
P{GD12574}
(Dickson et al., 2007.7.18, FlyBase, 1996-)
S-DKD
(Dickman et al., 2012)
damtRNAi
(Dickman et al., 2012)
snapin RNAi
(Wentzel et al., 2018)
Secondary FlyBase IDs
    References (11)