FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-APP.Aβ42.E693G.VTR}
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General Information
Symbol
P{UAS-APP.Aβ42.E693G.VTR}
FlyBase ID
FBtp0064419
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\APPAβ42.E693G.UAS.VTR
Size
Expression Data
Associated insertion(s)
3 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\APPAβ42.E693G.UAS.VTR
Transgenic product class
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\APP
Description

UAS drives expression of the 42 amino acid Aβ fragment from Hsap\APP carrying the familial Alzheimer's "Arctic" mutation (E693G - amino acid numbering based on Hsap\APP sequence).

(Singh and Mahoney, 2011.2.17)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (2)
Stocks containing insertion(s) of this recombinant construct
Bloomington
33774
w1118; P{UAS-APP.Aβ42.E693G.VTR}8
33773
y1 w1118; P{UAS-APP.Aβ42.E693G.VTR}4
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (19)
Reported As
Symbol Synonym
Aβ-arctic
(Huang et al., 2022)
Aβarc
(Uras et al., 2021)
P{UAS-APP.Abeta42.E693G.VTR}
(Singh and Mahoney, 2011.2.17)
P{UAS-APP.Aβ42.E693G.VTR}
(FlyBase, 1992-)
UAS Aβ
(Bajad et al., 2025)
UAS-APPE693G
(Uras et al., 2021)
UAS-Abeta42
(Tower et al., 2019)
UAS-Arctic
(Hsiao et al., 2025)
UAS-Arcβ42
(Khanal et al., 2024)
UAS-AΒ2E693G
(Yeh et al., 2018)
UAS-Aβ42
(Oyarce-Pezoa et al., 2023)
UAS-Aβ42-arctic
(Demirev et al., 2019)
UAS-Aβ42.E693G Arctic
(Oyarce-Pezoa et al., 2023)
UAS-Aβ42arc
(Ray et al., 2017)
UAS-Aβ42arc
(Fujii et al., 2025)
UAS-Aβ42E693G
(Panchal and Tiwari, 2020)
UAS:Aβ42 1-42E693G
(Rallis et al., 2020)
UASAβ
(Sharma et al., 2025)
UASAβ42Arc
(Breda et al., 2016)
Secondary FlyBase IDs
    References (19)