UAS regulatory sequences drive expression of the RE28911 cDNA carrying insertion mutations after the start codon of both the SclA and SclB open reading frames, resulting in a frameshift in each open reading frame. The frameshifts give rise to peptides of the same size but of a completely different sequence (MAKPATCSPPLASWPSCFSSSTSSMHM and MMRQKVCSPPSSSWPSCCSCSMPSTKAS) to wild type.
UAS regulatory sequences drive expression of the RE28911 cDNA carrying insertion mutations after the start codon of both the SclA and SclB open reading frames, resulting in a frameshift in each open reading frame. The frameshifts give rise to peptides of the same size but of a completely different sequence (MAKPATCSPPLASWPSCFSSSTSSMHM and MMRQKVCSPPSSSWPSCCSCSMPSTKAS) to wild type.