FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-TARDBP.ΔRRM1.NLSmut.M337V}
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General Information
Symbol
P{UAS-TARDBP.ΔRRM1.NLSmut.M337V}
FlyBase ID
FBtp0096141
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\TARDBPΔRRM1.NLSmut.M337V.UAS
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\TARDBPΔRRM1.NLSmut.M337V.UAS
Transgenic product class
inframe_deletion
(Ihara et al., 2013)
missense_variant
(Ihara et al., 2013)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\TARDBP
Description

UAS regulatory sequences drive expression of a mutant form of Hsap\TARDBP containing the familial-ALS linked mutation M337V and lacking the RNA recognition motif ((residues 106-175)) and NLS sequence (six basic amino acids (K82A, R83A, K84A, K95A, K97A, R98A) have been replaced with alanine).

(Ihara et al., 2013)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-TARDBP.ΔRRM1.NLSmut.M337V}
(FlyBase, 1992-)
UAS-TARDBP.ΔRRM1.NLSmut.M337V
(Pandey et al., 2025)
UAS-hTDP-43.NLSmut.ΔRRM1..M337V
(Pandey et al., 2025)
Secondary FlyBase IDs
    References (4)