FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-cic::hryDUX4.F}
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General Information
Symbol
P{UAS-cic::hryDUX4.F}
FlyBase ID
FBtp0117329
Feature type
transgenic_transposable_element
Component Allele(s)
cic::Hsap\DUX4UAS.cFa
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele cic::Hsap\DUX4UAS.cFa
Transgenic product class
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cic::Hsap\DUX4
Description

UASt regulatory sequences drive expression of a chimeric protein consisting of most of cic (amino acids 1-1380) including the C1 domain, fused to the C-terminal portion (amino acids 325-424) of Hsap\DUX4. The composition of this chimeric protein mirrors oncogenic CIC-DUX4 fusion chimeras associated with Ewing-like sarcomas in humans.

(Forés et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-cic::hDUX4.F}
(FlyBase, 1992-)
P{UAS-cic::hryDUX4.F}
(FlyBase, 1996-)
UAS-CIC-DUX4
(Forés et al., 2017)
Secondary FlyBase IDs
    References (4)