FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: PBac{UAS-hATXN3.tr.Q70.cc0}
Open Close
General Information
Symbol
PBac{UAS-hATXN3.tr.Q70.cc0}
FlyBase ID
FBtp0132178
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\ATXN3tr.Q70.cc0.UAS.Tag:HA,Tag:MYC
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\ATXN3tr.Q70.cc0.UAS.Tag:HA,Tag:MYC
Transgenic product class
inframe_deletion
(Kwon et al., 2018)
missense_variant
(Kwon et al., 2018)
trinucleotide_repeat_expansion
(Kwon et al., 2018)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\ATXN3
Tagged with
Tag:HA
Tag:MYC
Description

UAS regulatory sequences drive expression of a truncated form of Hsap\ATXN3, consisting of a Q repeat region of 70 residues flanked upstream by 14 amino acids and downstream by 43 amino acids. The Q repeat region contains only α-helical coiled-coil structures, and lacks β-sheet motifs due to the insertion of Q to N and Q to E β-sheet-breaking mutations. The protein is tagged at the N-terminal end with Tag:HA and at the C-terminal end with Tag:MYC.

(Kwon et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PBac{UAS-hATXN3.tr.Q70.cc0}
(FlyBase, 1992-)
UAS-MJDtr-70Q_cc0
(Kwon et al., 2018)
Secondary FlyBase IDs
    References (3)