FB2026_03 , released September 17, 2026
Recombinant Construct: PBac{UAS-N.ΔEGF1-18.LNR}
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General Information
Symbol
PBac{UAS-N.ΔEGF1-18.LNR}
FlyBase ID
FBtp0149460
Feature type
transgenic_transposable_element
Component Allele(s)
NΔEGF1-18.LNR.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele NΔEGF1-18.LNR.UAS
Transgenic product class
inframe_deletion
(Salazar et al., 2021)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
N
Description

UASt regulates expression of a ligand-independent form of N that still depends on ADAM10 and gamma-secretase by deleting several epidermal growth factor-like (EGF) repeats of the extracellular domain that contains the ligand binding domain and Lin-12/Notch Repeats (LNR) within the negative regulatory region. FlyBase curator comment: the expressed protein is not tagged with HA even though the transgene was generated using the pUASg-HA.attB plasmid, as the ORF contains a stop codon (see FBrf0252879).

(Salazar et al., 2021)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
94072
y1 w*; PBac{UAS-N.ΔEGF1-18.LNR}VK00037/SM6a
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PBac{UAS-N.ΔEGF1-18.LNR}
(FlyBase, 1992-)
UAS-NΔEGF1-18.LNR
(Salazar et al., 2021)
Secondary FlyBase IDs
    References (3)