FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term fibroblast growth factor receptor signaling pathway ID (Ontology) GO:0008543 (Gene Ontology)
Definition The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
Also Known As"FGF receptor signaling pathway" ; "FGF receptor signalling pathway" ; "FGFR signaling pathway" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 fibroblast growth factor receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)
     acts_upstream_of_positive_effect | fibroblast growth factor receptor signaling pathway       --
     involved_in | fibroblast growth factor receptor signaling pathway       --
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enzyme-linked receptor protein signaling pathway
 |__cell surface receptor protein tyrosine kinase signaling pathway__
cellular response to growth factor stimulus                          |
 |__cellular response to fibroblast growth factor stimulus___________|
response to fibroblast growth factor                                 |
 |__cellular response to fibroblast growth factor stimulus___________|
                                                                     fibroblast growth factor receptor signaling pathway  43 rec.
                                                                      |__fibroblast growth factor receptor apoptotic signaling pathway
                                                                      |__fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment
                                                                      |__fibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                      |__fibroblast growth factor receptor signaling pathway involved in mammary gland specification
                                                                      |__fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
                                                                      |__fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
                                                                      |__fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
                                                                      |__fibroblast growth factor receptor signaling pathway involved in somitogenesis
                                                                      |__negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway
                                                                      |__positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
                                                                      |__positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway
                                                                      |__regulation of fibroblast growth factor receptor signaling pathway 16 rec.
                                                                          |__negative regulation of fibroblast growth factor receptor signaling pathway 9 rec.
                                                                          |__positive regulation of fibroblast growth factor receptor signaling pathway 8 rec.
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Is a cell surface receptor protein tyrosine kinase signaling pathway
Part of cellular response to fibroblast growth factor stimulus
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Synonyms
  • "FGF receptor signaling pathway" EXACT
    "FGF receptor signalling pathway" EXACT
    "FGFR signaling pathway" EXACT
    "fibroblast growth factor receptor signalling pathway" EXACT
Secondary IDs
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Reactome:R-HSA-190236 "Signaling by FGFR"