FB2025_01 , released February 20, 2025
Allele: Dmel\gbbRNAi.UAS.cBa
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General Information
Symbol
Dmel\gbbRNAi.UAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ballard
FlyBase ID
FBal0244083
Feature type
allele
Associated gene
Dmel\gbb
Associated Insertion(s)
Carried in Construct
P{UAS-gbb.RNAi.B}
Key Links
Transgenic product class
RNAi_reagent
(Ballard et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ballard et al., 2010)
Mutagen
in vitro construct
(Ballard et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-gbb.RNAi.B}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat corresponding to an approximately 400 bp region of gbb.

(Ballard et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
gbb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4D42, gbbdsRNA.Scer\UAS.cBa larvae display wildtype numbers of boutons at neuromuscular junctions 6/7 and 4.

      Larvae expressing gbbdsRNA.Scer\UAS.cBa under the control of Scer\GAL4how-24B display a 28% decrease in the number of boutons at both neuromuscular junction (NMJ) 6/7 and at NMJ 4.

      (James and Broihier, 2011)

      Third instar larvae expressing gbbdsRNA.Scer\UAS.cBa driven by either Scer\GAL4fat or Scer\GAL4ppl.PP are transparent and show increased uptake and transport of ingested fluorescently labeled fatty acids from the midgut lumen to the fat body compared to wild-type controls.

      (Ballard et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4D42-mediated expression of gbbdsRNA.Scer\UAS.cBa suppresses the neuromuscular junction expansion phenotype seen in cmpyΔ8 mutants.

      (James and Broihier, 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      gbbRNAi.UAS.cBa
      gbbdsRNA.Scer\UAS.cBa
      gbbdsRNA.UAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ballard
      Secondary FlyBase IDs
        References (3)